Controlled approach generates furosemide polymorphs via crystallization with pyridine derivatives, suggesting implications for drug design.
A controlled two-step approach for generating furosemide polymorphs through multicomponent crystal formation followed by desolvation was investigated. Furosemide was crystallised with five pyridine derivatives-pyridine (FUR.PYRw), 3-picoline (FUR.3PIC), 4-picoline (FUR.4PIC), 2,3-lutidine...
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Nomnganga et al. (2025) studied this question.
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