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December 6, 2025JAC-Antimicrobial ResistanceOpen Access

P32 Carbapenem-resistant Acinetobacter spp as a major pathogen in early-onset neonatal sepsis among hospitalized neonates in southern Pakistan

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Authors

FMFatima MirSSSadia Shakoor

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Overview

Analysis reveals that 22% of early-onset neonatal sepsis is due to carbapenem-resistant Acinetobacter in southern Pakistan, suggesting urgent need for new antibiotics.

Key Points

  • Acinetobacter spp emerged as the leading pathogen causing early-onset neonatal sepsis, comprising 22% of cases.
  • Among carbapenem-resistant Acinetobacter, 72% were multidrug resistant, highlighting severe treatment challenges.
  • Data analysis involved blood cultures from over 45,000 neonates processed in a central laboratory from 2018 to 2022.
  • High levels of drug resistance in pathogens call for further research into effective treatment options in neonatal care.

Cite This Study

Mir et al. (2025) studied this question.

synapsesocial.com/papers/69337d09b3f947a0a125ac7chttps://doi.org/10.1093/jacamr/dlaf230.039
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