Framing Theranostic Protocols: Development, Implementation, and Insights from Clinical Practice

Technologists are increasingly responsible for complex theranostic procedures, yet formal training and standardized protocols remain limited. This article outlines the development and implementation of detailed protocols at Oregon Health & Science University to support patient care, regulatory compliance, staff training, and reproducible workflows for therapy administration and imaging. Protocols were developed through collaboration among technologists, physicians, nurses, and physicists to ensure adaptability and consistency. Key considerations include delineation of responsibilities between nursing and technologist staff and flexibility in administration techniques on the basis of patient needs and institutional resources. The protocols provided herein serve as practical examples for institutions initiating or expanding theranostic services and contribute to broader efforts toward standardization across the field.