December 8, 2025Addiction BiologyOpen Access

The Addiction Neurocircuitry and Resting‐State Functional Connectivity in Cannabis Use Disorder: An fMRI Study

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fMRI study reveals altered resting-state functional connectivity in cannabis use disorder, indicating links to substance use and depression symptoms.

Altered resting-state functional connectivity was observed in cannabis use disorder participants, enhancing understanding of the neurocircuitry involved.
The CUD group showed significant differences compared to controls, highlighting the unique neurobiological changes associated with addiction.
Analysis using fMRI explored the connections between brain regions responsible for reward processing and disinhibition.
Findings suggest deeper insights into neurobiology trends in cannabis use disorder and emphasize the need for targeted interventions.

Thomson et al. (2025) studied this question.

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fMRI study reveals altered resting-state functional connectivity in cannabis use disorder, indicating links to substance use and depression symptoms.