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December 8, 2025Journal of Cellular and Molecular MedicineOpen Access

Revealing Causal Protein Biomarkers and Potential Therapeutic Targets for Histologic‐Specific Lung Cancer

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Authors

JLJingyang LiuLWLijuan WuXWXiao Wang

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Overview

Cohort study reveals therapeutic targets and protein biomarkers in lung cancer, suggesting new prevention strategies and drug repurposing.

Key Points

  • Lung cancer therapeutic targets were identified, indicating potential for drug repurposing.
  • A total of 47,000 participants' blood samples were analyzed for 2,923 proteins, associating with subtypes.
  • Mendelian randomisation and logistic regression approaches pinpointed key proteins like GP1BA, ACADSB, and ITGB2.
  • Highlights the need for tailored prevention strategies based on distinct lung cancer subtypes.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/693624984fa91c937236c1abhttps://doi.org/10.1111/jcmm.70866
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