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This is a In Vitro Study study.

December 8, 2025Frontiers in PharmacologyOpen Access

Xiaoyao Pill alleviates ulcerative colitis by inhibiting ferroptosis of enterocytes via activating Nrf2/Gpx4 signaling pathway

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Analysis shows Xiaoyao Pill reduces cytokines and oxidative stress in ulcerative colitis, suggesting benefits for intestinal health.

Xiaoyao Pill significantly reduces IL-1β and IL-6 levels in ulcerative colitis, improving intestinal permeability and enterocyte health.
Findings show that XYP enhances antioxidant enzymes and decreases oxidative stress markers in DSS-treated mice.
Transcriptomic analysis identifies pathways influenced by XYP, particularly Nrf2 and Gpx4 participation in ferroptosis inhibition.
This study highlights the potential of XYP to serve as a therapeutic agent for ulcerative colitis management.

Xiaoqing Zhang (2025) studied this question.

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December 8, 2025Frontiers in PharmacologyOpen Access

View Full Paper

Ask AI

Bookmark

Authors

Analysis shows Xiaoyao Pill reduces cytokines and oxidative stress in ulcerative colitis, suggesting benefits for intestinal health.

Xiaoyao Pill significantly reduces IL-1β and IL-6 levels in ulcerative colitis, improving intestinal permeability and enterocyte health.
Findings show that XYP enhances antioxidant enzymes and decreases oxidative stress markers in DSS-treated mice.
Transcriptomic analysis identifies pathways influenced by XYP, particularly Nrf2 and Gpx4 participation in ferroptosis inhibition.
This study highlights the potential of XYP to serve as a therapeutic agent for ulcerative colitis management.

Xiaoqing Zhang (2025) studied this question.

View Full Paper

Ask AI

Bookmark