Ethanol sclerotherapy for endometriomas: a fertility-preserving alternative

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Discussion

Evidence reveals ethanol sclerotherapy improves ovarian reserve in women with endometriomas, suggesting it may be a safer alternative to cystectomy.

Ethanol sclerotherapy preserves ovarian reserve, providing a viable option for managing endometriomas with minimal trauma.
The technique is associated with low rates of major complications and offers effective pain relief post-procedure.
Observational studies highlight comparable pregnancy rates between sclerotherapy and cystectomy, with some indicating higher oocyte yield.
Future randomized controlled trials are essential for evaluating long-term efficacy and cost-effectiveness relative to other treatments.

Younis et al. (2025) studied this question.

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Evidence reveals ethanol sclerotherapy improves ovarian reserve in women with endometriomas, suggesting it may be a safer alternative to cystectomy.