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December 4, 2025Rheumatology and TherapyOpen Access

Filgotinib Effectiveness in Rheumatoid Arthritis: Observational Analysis of a Large Multicenter Cohort

Eleonora Celletti Myriam Di Penta Simone Parisi Aldo Biagio Molica Colella Marta Priora Federica Lumetti Rosetta Vitetta Fabio Mascella Maria Cristina Focherini Alessia Fiorenza Gianluca Smerilli Gerolamo Bianchi Eugenio Arrigoni Riccardo Bixio

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Key Points

A significant DAS28-CRP response was observed in patients receiving treatment.
This analysis demonstrated effective treatment response among a large cohort with rheumatoid arthritis.
Observational analysis across multiple centers assessed filgotinib treatment outcomes in a real-world setting.
Findings highlight the importance of real-world data in evaluating rheumatoid arthritis therapies.

Implication

Observational analysis shows effectiveness of filgotinib in rheumatoid arthritis, suggesting improved patient outcomes.

Abstract

This analysis of real-world patients with RA demonstrated the effectiveness of FIL with a good DAS28-CRP response and high DRR at follow-up.

Discussion

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Cite This Study

Celletti et al. (2025) studied this question.

synapsesocial.com/papers/693624ad4fa91c937236c53f https://doi.org/10.1007/s40744-025-00805-2

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1AB0589 FILGOTINIB IN ACTION: REAL-WORLD INSIGHTS FROM A BELGIAN REGISTRY OF PATIENTS WITH RHEUMATOID ARTHRITIS2024
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4Efficacy/Effectiveness, Safety and Treatment Persistence of Filgotinib in Rheumatoid Arthritis: A Narrative Review of Clinical Trials and Real-World EvidenceLiterature Review · 2026
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