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December 8, 2025Therapeutic Advances in Medical OncologyOpen Access

NAB-paclitaxel and cisplatin versus gemcitabine and cisplatin as induction chemotherapy in locoregionally advanced nasopharyngeal carcinoma: a retrospective, propensity score-matched analysis

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YLYou‐Ping LiuSun Yat-sen University

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Retrospective analysis shows comparable effectiveness in progression-free survival for NAB-paclitaxel versus gemcitabine in locoregionally advanced nasopharyngeal carcinoma.

Key Points

NAB-paclitaxel and cisplatin showed comparable survival outcomes in locoregionally advanced nasopharyngeal carcinoma patients, despite differing toxicity profiles.
In a matched cohort of 197 patients, the NAB-TP regimen indicated lower incidences of anemia compared to the gemcitabine regimen.
Propensity score-matched analysis conducted to adjust for confounding factors yielded no significant differences in 5-year progression-free survival.
Chemoradiotherapy following NAB-TP induction chemotherapy appears to maintain efficacy while reducing acute toxicity among treated individuals.

Cite This Study

You‐Ping Liu (2025) studied this question.

synapsesocial.com/papers/693624ad4fa91c937236c752 https://doi.org/10.1177/17588359251400977

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Implication

Retrospective analysis shows comparable effectiveness in progression-free survival for NAB-paclitaxel versus gemcitabine in locoregionally advanced nasopharyngeal carcinoma.

NAB-paclitaxel and cisplatin versus gemcitabine and cisplatin as induction chemotherapy in locoregionally advanced nasopharyngeal carcinoma: a retrospective, propensity score-matched analysis

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Implication

Key Points

Cite This Study

NAB-paclitaxel and cisplatin versus gemcitabine and cisplatin as induction chemotherapy in locoregionally advanced nasopharyngeal carcinoma: a retrospective, propensity score-matched analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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