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December 8, 2025International Journal of SurgeryOpen Access

Revealing the mechanism of chanling Gao in preventing and treating liver metastasis in colorectal cancer through integrated multi-omics and artificial intelligence

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Authors

LJLi JHSHaiqiao SunALAi-Ling Liang

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Overview

Integrated multi-omics approach reveals binding affinity of Chanling Gao in colorectal cancer liver metastasis, highlighting AI's role in prognostic modeling.

Key Points

  • Colorectal cancer treatment improved through a model demonstrating a high binding affinity of CLG components to TP53.
  • Prognostic models using Non-Negative Matrix Factorization identified key subtypes exhibiting distinct survival outcomes.
  • Network pharmacology was used to elucidate the mechanisms of CLG in colorectal cancer liver metastasis using machine learning techniques.
  • This analysis underscores the potential clinical applications of CLG and advanced AI models in colorectal cancer management.

Cite This Study

J et al. (2025) studied this question.

synapsesocial.com/papers/693624ba4fa91c937236c880https://doi.org/10.1097/js9.0000000000004322
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