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December 8, 2025Science ProgressOpen Access

The relationship between epicardial adipose tissue and premature ventricular contractions originating from different areas in the right ventricular outflow tract: A cross-sectional study

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Authors

HYHao YaoJCJian ChenXLXueling Li

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Overview

Cross-sectional study reveals epicardial adipose tissue's role in PVCs from the right ventricular outflow tract, highlighting links to BMI and sex differences.

Key Points

  • Patients with PVCs from the RVOT free wall had significantly higher epicardial adipose tissue volume compared to those from the RVOT septum, indicating distinct pathophysiology.
  • Subgroup analyses identified that females and patients with lower BMI in the free wall group showed larger EAT volumes than counterparts with septal PVCs.
  • Comparative assessments utilized chest CT imaging to measure EAT volume and density in PVC patients undergoing catheter ablation between Jan 2022 and Jun 2024.
  • Study findings suggest that EAT's pathogenicity in PVCs may vary based on anatomical origin and demographic factors like sex and body mass index.

Cite This Study

Yao et al. (2025) studied this question.

synapsesocial.com/papers/693624ba4fa91c937236ca24https://doi.org/10.1177/00368504251404083
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Relationship between epicardial adipose tissue measured by computed tomography and premature ventricular complexes originating from different sites2023 · 19 citations
  2. 2The relationship between frequent premature ventricular complexes and epicardial adipose tissue volume2023 · 3 citations
  3. 3Epicardial Adipose Tissue Thickness is Higher in Right Ventricular Outflow Tract Tachycardia2021
  4. 4Epicardial Fat Distribution Assessed with Cardiac CT in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy2018 · 24 citations
  5. 5THE RELATIONSHIP BETWEEN EPICARDIAL FAT TISSUE THICKNESS AND RISK OF FREQUENT PREMATURE VENTRICULAR CONTRACTIONS2021