December 8, 2025AntibioticsOpen Access

Detection of ARGs from Gram-Negative Bacteria in Positive Blood Cultures Using a Microarray-Based System: Towards a Molecular Antibiotic Susceptibility Assay

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Analysis using microarray assay identifies antimicrobial resistance genes in Escherichia coli, highlighting the need for rapid diagnostic tools.

High agreement in detecting sulfonamides and β-lactams resistance genes in positive blood cultures.
A microarray assay was applied to 111 Gram-negative bacterial isolates, showcasing its diagnostic ability.
Antimicrobial resistance genes were effectively identified, though some false negatives were noted among isolates.
Broad coverage of the assay supports rapid antimicrobial stewardship, indicating its potential for future use.],

Fiori et al. (2025) studied this question.

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Analysis using microarray assay identifies antimicrobial resistance genes in Escherichia coli, highlighting the need for rapid diagnostic tools.