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December 8, 2025Gastroenterology InsightsOpen Access

Clinical and Endoscopic Features of Upper Gastrointestinal Bleeding Associated with Helicobacter pylori Infection: A Retrospective Cohort Study in the Colombian Caribbean (2021–2023)

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Authors

ABAndrés Cadena BonfantiADAlex Domínguez-Vargas

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Overview

Retrospective cohort study shows hypertension and chronic gastritis linked to Helicobacter pylori in upper gastrointestinal bleeding cases, highlighting clinical features for early detection.

Key Points

  • This study aimed to describe the incidence and clinical-endoscopic features of Helicobacter pylori associated with upper gastrointestinal bleeding in Barranquilla, Colombia.
  • Conducted a retrospective cohort study of adults admitted for upper gastrointestinal bleeding from 2021 to 2023
  • Collected demographic, clinical, and endoscopic data from institutional records
  • Applied non-parametric tests to compare sex and admission diagnosis
  • Utilized multiple correspondence analysis to explore associations among clinical and pathological parameters
  • 44 out of 329 UGIB patients (13%) tested positive for Helicobacter pylori
  • Median age of affected patients was 60 years, with 57% being male
  • Melena (48%) and hematemesis (45%) were the primary presenting symptoms
  • Chronic gastritis was the most common histopathological finding in 75% of cases

Cite This Study

Bonfanti et al. (2025) studied this question.

synapsesocial.com/papers/693624ce4fa91c937236cda2https://doi.org/10.3390/gastroent16040048
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