Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2025BloodOpen Access

Trends in mortality from deep vein thrombosis and pulmonary embolism as multiple causes of death in u.S. adults aged ≥65 years (1999–2023): A CDC wonder analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

HWHakim WazirNTNayanika TummalaASAdnan Sharif

Discussion

Loading...

Member takes

Overview

Analysis shows rising mortality rates from DVT and PE in older adults, indicating significant health disparities.

Key Points

  • This research examines mortality trends from deep vein thrombosis and pulmonary embolism among U.S. adults aged 65 and older.
  • Analyzed mortality data from the CDC WONDER database (1999–2023) using ICD-10 codes for DVT and PE.
  • Calculated age-adjusted mortality rates (AAMRs) per 100,000 for older adults, stratified by various demographics.
  • Employed joinpoint regression to estimate average annual percent change (AAPC) with statistical significance.
  • 76,055 deaths attributed to DVT and PE among adults aged ≥65 occurred from 1999 to 2023.
  • The AAMR increased from 5.59 to 6.94 per 100,000, with a notable rise among males and NH Blacks.
  • Significant mortality differences were found based on geography and urbanization.

Cite This Study

Wazir et al. (2025) studied this question.

synapsesocial.com/papers/69362f604fa91c937236dd28https://doi.org/10.1182/blood-2025-7993
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Trends and Disparities in Pulmonary Embolism Mortality in the United States, 1999– 20232025
  2. 2C28-21 Trends in Pulmonary Embolism-related Mortality Among Patients With Pneumonia in the United States: A CDC Wonder Analysis (1999-2023)2026
  3. 3Temporal trends in hypertension and pulmonary embolism–related mortality in the United States: A population-based study using CDC WONDER, 2000–20202025
  4. 4Mortality trends in the United States for adults with concurrent cerebrovascular disease and pulmonary embolism2026
  5. 5Trends and Disparities in Mortality due to Pulmonary Embolism Among Adults With Atrial Fibrillation From 1999 to 2020: Insights From the <scp>CDC</scp> <scp>WONDER</scp> Database2026