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December 8, 2025BloodOpen Access

In-hospital stroke, myocardial infarction, and venous thrombosis in immune thrombocytopenia: Incidence, risk factors, and outcomes from a national cohort

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Authors

KSKunal SharmaADAbhizith DeokerMPManas Pustake

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Overview

Retrospective cohort study reveals higher mortality and risk factors like obesity and comorbidities in hospitalized ITP patients.

Key Points

  • This study aims to evaluate the incidence and risk factors for thrombotic events in hospitalized ITP patients.
  • Retrospective cohort analysis of 23,046 hospitalized adults with ITP from national database.
  • Thrombotic events identified via validated ICD-10-CM codes, with structured data abstraction for outcomes.
  • Statistical methods included multivariable logistic regression for adjusted odds ratios.
  • Thrombosis occurred in 7.9% of hospitalized ITP patients, linked to higher mortality and longer hospital stays.
  • Identified risk factors included older age, obesity, SLE, antiphospholipid syndrome, and solid tumors.

Cite This Study

Sharma et al. (2025) studied this question.

synapsesocial.com/papers/69362f634fa91c937236ddeahttps://doi.org/10.1182/blood-2025-4473
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