Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2025BloodOpen Access

Operational cure in patients with newly diagnosed multiple myeloma after autologous stem cell transplantation: Long-term survivors and impact of induction regimens.

View Full Paper
Ask AI
Bookmark
Share

Authors

FFFrancesc Fernández-AvilésCLCarlos Fernández de LarreaNTNatalia Tovar

Discussion

Loading...

Member takes

Overview

Retrospective analysis shows improved complete response rates and survival in patients with NDMM after autologous stem cell transplantation, indicating benefits of novel induction regimens.

Key Points

  • To identify long-term survival rates and the impact of induction regimens on outcomes in patients with newly diagnosed multiple myeloma after transplantation.
  • Retrospective analysis of NDMM patients who underwent ASCT as first line therapy
  • Data collected included patient characteristics, treatment regimens, and outcomes
  • Statistical analysis performed using STATAv16.1 and RStudio
  • 12% of patients remained alive with sustained complete response at 10 years post-transplant
  • Higher complete response rates observed with novel agent induction compared to chemotherapy
  • Median overall survival was 94 months and progression-free survival was 34.9 months in the study cohort

Cite This Study

Fernández-Avilés et al. (2025) studied this question.

synapsesocial.com/papers/69362f714fa91c937236e176https://doi.org/10.1182/blood-2025-5776
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1P24 | APPROACHING CURE IN MULTIPLE MYELOMA: A DUAL-CENTER EXPERIENCE AMONG PATIENTS DIAGNOSED BEFORE 20102026 · 1 citations
  2. 2Profile of NDMM patients who remain progression free at 10 years treated with RVD induction and risk adapted maintenance2025
  3. 3Multiple myeloma patients with a long remission after autologous hematopoietic stem cell transplantation2024 · 20 citations
  4. 4Impact of second autologous stem‐cell transplantation at relapsed multiple myeloma: A French multicentric real‐life study2024 · 3 citations
  5. 5P54 | EVOLVING OUTCOMES IN MULTIPLE MYELOMA REAL-WORLD PRACTICE: 30-YEARS SINGLE CENTER EXPERIENCE2026