Multicenter study reveals a risk prediction model for early death in multiple myeloma patients, suggesting timely interventions based on clinical parameters.
Key Points
To develop and validate a risk prediction model for early mortality in multiple myeloma patients with renal impairment.
Multicenter retrospective analysis of newly diagnosed MM patients with renal impairment
Logistic regression with backward selection to identify predictors
Development of a nomogram; validation through Harrell's C-index and ROC analysis.
Identified five independent predictors of early mortality.
Developed a nomogram with AUC 0.858 for excellent discrimination in predicting risk.
Categorized patients into low, mid, and high risk for early mortality.