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December 8, 2025Blood

Therapeutic outcomes of glofitamab-based regimens in Chinese patients with Relapsed/Refractory B-cell lymphoma: A single-center retrospective real-world study

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Authors

JSJing Sui

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Overview

Retrospective analysis indicates glofitamab improves response rates in Chinese patients with R/R B-cell lymphoma, suggesting a promising treatment option.

Key Points

  • Evaluating the therapeutic outcomes of glofitamab-based regimens in Chinese patients with relapsed/refractory B-cell lymphoma.
  • Conducted a single-center retrospective study in a Chinese hospital.
  • Enrolled patients with R/R B-cell lymphoma receiving glofitamab-based therapy.
  • Collected comprehensive clinical data, including treatment details and adverse events.
  • Among 20 patients, the overall response rate was 92.8%, with a 35.7% complete response rate.
  • Treatment included glofitamab monotherapy and combination regimens with chemotherapy.
  • Reported adverse events included grade 1 cytokine release syndrome in 7 patients and grade 3 lymphopenia in 12 patients.

Cite This Study

Jing Sui (2025) studied this question.

synapsesocial.com/papers/69362f744fa91c937236e284https://doi.org/10.1182/blood-2025-7204
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