Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2025Blood

In-hospital outcomes of hyponatremia in non-Hodgkin lymphoma patients: Insights from a 7-year national cohort study

View Full Paper
Ask AI
Bookmark
Share

Authors

MJM K JavaidFAFaizan AhmedTMTehmasp Rehman Mirza

Discussion

Loading...

Member takes

Overview

Retrospective analysis reveals hyponatremia increases mortality and hospital stay in non-Hodgkin lymphoma patients, suggesting need for improved management.

Key Points

  • This research aims to evaluate the impact of hyponatremia on clinical outcomes in patients with non-Hodgkin lymphoma.
  • Retrospective study conducted using the NIS database (2016-22)
  • Patients with non-Hodgkin lymphoma were categorized based on presence of hyponatremia
  • Included demographic variables, socioeconomic indicators, and comorbidity burden via the Charlson Comorbidity Index
  • Outcomes assessed included in-hospital mortality, length of stay, and total charges utilizing logistic and linear regression models
  • 14% of 260,210 hospitalized patients with non-Hodgkin lymphoma had hyponatremia
  • Hyponatremic patients had higher mortality (OR: 2.04) and longer hospital stays (β=4.13)
  • Significant increases in total charges for hyponatremic patients ($57,421) compared to non-hyponatremic
  • Hyponatremia prevalence increased from 10.9% to 17.2% over seven years

Cite This Study

Javaid et al. (2025) studied this question.

synapsesocial.com/papers/69362f744fa91c937236e315https://doi.org/10.1182/blood-2025-8051
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The occurrence of hyponatremia and its importance as a prognostic factor in a cross-section of cancer patients2016 · 92 citations
  2. 2Evaluating the association between hyponatremia and prognosis in hospitalized patients with cancer.2025
  3. 3Impact of hyponatremia on multiple myeloma hospitalizations: A nationwide analysis.2024
  4. 4Prevalence of hyponatremia among medically hospitalized patients and associated outcomes: a retrospective cohort study2024 · 7 citations
  5. 5Evaluation of incremental healthcare resource burden and readmission rates associated with hospitalized hyponatremic patients in the US2012 · 52 citations