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November 3, 2025BloodOpen Access

Smartphone app for noninvasive, at-home pediatric hemoglobin monitoring in sickle cell disease.

K.G.S. Rana Wilbur A. Lam Inga Hegemann Psalm Inusa Janne Toftegaard Madsen Erika A. Tyburski

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Key Points

This research aims to evaluate a smartphone app for noninvasive hemoglobin monitoring in children with sickle cell disease.
Enrolled 30 pediatric participants with sickle cell disease.
Participants took app tests and received venous blood tests over 12 weeks.
App performance was evaluated for mean absolute error and compliance rates.
Mean absolute error of the app was ±0.57 g/dL, indicating strong accuracy.
85% compliance in test usage among participants during the study's initial weeks.
The app's noninvasive nature was positively received by participants and caregivers.

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Implication

Research demonstrates a smartphone app accurately measures hemoglobin in pediatric sickle cell disease, suggesting improved monitoring solutions.

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Cite This Study

Rana et al. (2025) studied this question.

synapsesocial.com/papers/69362f7d4fa91c937236e48a https://doi.org/10.1182/blood-2025-1158

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