Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2025Blood

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) international registry: Assessment of the allo-HCT outcomes

View Full Paper
Ask AI
Bookmark
Share

Authors

MBMaria BadikyanCPChing‐Tien PengHGHasanein H. Ghali

Discussion

Loading...

Member takes

Overview

International registry reports improved survival outcomes from allo-HCT in patients with BPDCN, indicating risks and responses to treatments like venetoclax and chemotherapy.

Key Points

  • Evaluate outcomes of allogeneic hematopoietic stem cell transplantation in patients with BPDCN.
  • Data collected retrospectively and prospectively from 17 medical centers worldwide.
  • Patients' characteristics, diagnostics, treatment options and responses evaluated.
  • Outcomes assessed for patients who underwent allo-HCT.
  • 16 patients out of 70 underwent allo-HCT with median age of 49 years.
  • Completeness of diagnosis via bone marrow examination confirmed in 81.25% of cases.
  • 63% of patients were alive at median follow-up of 27 months, with relapses noted in four patients.

Cite This Study

Badikyan et al. (2025) studied this question.

synapsesocial.com/papers/69362f7f4fa91c937236e534https://doi.org/10.1182/blood-2025-2518
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Allogeneic hematopoietic cell transplantation as the standard of care for blastic plasmacytoid dendritic cell neoplasm in first complete remission.2025
  2. 2Blastic plasmacytoid dendritic cell neoplasm: a Swiss case series of a very rare disease and a structured review of the literature2025
  3. 3Real-world study of treatment landscape and safety outcomes of US patients with blastic plasmacytoid dendritic cell neoplasm2025 · 1 citations
  4. 4Single center retrospective evaluation of CHOP-based regimens in older patients with treatment naive blastic plasmacytoid dendritic cell neoplasm2025 · 1 citations
  5. 5Real-World Management of Blastic Plasmacytoid Dendritic Cell Neoplasm at an Academic Center with a Broad Regional Referral Base2025