retrospective review shows decline in sep-1 compliance in hospitals, suggesting need for balanced stewardship.
Timely blood cultures (BCx) are required by SEP-1. The recent BCx bottle shortage necessitated enhanced BCx stewardship. At two hospitals during the shortage, SEP-1 metric compliance declined related to BCx utilization. Review of cases where BCx were not obtained demonstrated most BCx were safely avoided without demonstrable patient harm.
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Ryder et al. (2025) studied this question.
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