What question did this study set out to answer?

To evaluate the relationship between SEP-1 compliance and blood culture utilization during a shortage.

December 12, 2025Open Access

Are SEP-1 and blood culture stewardship at odds? Retrospective review of SEP-1 failures pre- and during a blood culture bottle shortage

Key Points

To evaluate the relationship between SEP-1 compliance and blood culture utilization during a shortage.
Retrospective review conducted at two hospitals.
Examined cases of SEP-1 failures related to blood culture utilization.
Analyzed metrics pre- and during the blood culture bottle shortage.
Observed decline in SEP-1 compliance during blood culture shortage.
Most blood cultures were avoided without demonstrable patient harm.

Abstract

Abstract Timely blood cultures (BCx) are required by SEP-1. The recent BCx bottle shortage necessitated enhanced BCx stewardship. At two hospitals during the shortage, SEP-1 metric compliance declined related to BCx utilization. Review of cases where BCx were not obtained demonstrated most BCx were safely avoided without demonstrable patient harm.

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