What type of study is this?

This is a Case Report study (also classified as: Literature Review).

What question did this study set out to answer?

To report a rare case of coexisting Wilson's disease and autoimmune hepatitis in a pediatric patient.

December 12, 2025Journal of Clinical MedicineOpen Access

Wilson’s Disease with Autoimmune Hepatitis Manifestation in a Pediatric Patient: A Case Report and Literature Review

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Authors

NGNicoleta GimigaGrigore T. Popa University of Medicine and Pharmacy GPGabriela PăduraruGrigore T. Popa University of Medicine and Pharmacy LBLaura-Iulia BozomituGrigore T. Popa University of Medicine and Pharmacy

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Implication

Case report details dual diagnosis of autoimmune hepatitis and Wilson's disease using D-penicillamine in an 11-year-old girl, highlighting diagnostic challenges.

Key Points

To report a rare case of coexisting Wilson's disease and autoimmune hepatitis in a pediatric patient.
Clinical case presentation of an 11-year-old girl with abdominal pain and jaundice.
Medical and laboratory investigations confirming Wilson's disease and the use of D-penicillamine for treatment.
Liver biopsy and histochemical analysis to diagnose autoimmune hepatitis alongside Wilson's disease.
The patient demonstrated initial improvement with D-penicillamine treatment.
Subsequent acute hepatitis developed six weeks later after initial favorable clinical course.
Liver biopsy confirmed the presence of both Wilson's disease and autoimmune hepatitis, establishing a dual diagnosis.

Cite This Study

Gimiga et al. (2025) studied this question.

synapsesocial.com/papers/694019032d562116f28f60a7 https://doi.org/10.3390/jcm14248798

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Implication

Case report details dual diagnosis of autoimmune hepatitis and Wilson's disease using D-penicillamine in an 11-year-old girl, highlighting diagnostic challenges.

Wilson’s Disease with Autoimmune Hepatitis Manifestation in a Pediatric Patient: A Case Report and Literature Review

Discussion

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Implication

Key Points

Cite This Study

Wilson’s Disease with Autoimmune Hepatitis Manifestation in a Pediatric Patient: A Case Report and Literature Review

Discussion

Member takes

Implication

Key Points

Cite This Study

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