Retrospective observational study shows advance care planning reduces mechanical ventilation in high-risk older adults, indicating treatment strategy implications.
Background In March 2020, professional organizations issued guidelines for anticipatory COVID-19 advance care planning (aACP) with high-risk older adults. Objective To examine responses to these guidelines and associated COVID-19 treatment intensity. Design Retrospective regression discontinuity design (RDD) using 2020 Medicare Parts A and B claims to assess aACP receipt, by beneficiary COVID-19 mortality risk. Adjusted logistic regression to assess predictors of aACP and the association between aACP and COVID-related mechanical ventilation. Patients Medicare fee-for-service beneficiaries 66 and older enrolled on January 1, 2020. Main Measures ACP visits assessed via current procedural terminology billing codes 99497 and 99498: classified as anticipatory if the place of service was ambulatory and outside an annual wellness visit. COVID-19 mortality risks based on age and/or co-morbidity and practice attribution were assessed pre-lockdown. Hospitalization within 2 weeks of COVID-19 diagnosis and associated mechanical ventilation (MV) were assessed post-lockdown. Key Results In total, 24,935,234 beneficiaries received 470,046,404 encounters in 2020; 1,578,331 were for ACP; of these, 318,813 (20%) were classified as anticipatory. Lockdown abruptly decreased all encounters. The RDD estimate found aACP decreased by 54% (95% CI= −0.62, −0.46); the relative decline in aACP was smaller for highest COVID-19 mortality risk groups: multimorbidity (−42%; 95% CI= −0.48, −0.35), patients with advanced cancer (−44%; 95% CI= −0.52, −0.36), dementia (−35%; 95% CI= −0.43, −0.27), or ESRD (−38%; 95% CI= −0.55, −0.21). Care from an integrated health system was associated with less aACP. Among 1,314,986 beneficiaries diagnosed with COVID-19, aACP was associated with an increase in adjusted 14-day hospitalization (OR = 1.21; 95% CI=1.17–1.26) but a decrease in invasive mechanical ventilation if hospitalized (OR = 0.85; 95% CI=0.77–0.96). Conclusions Providers followed recommendations to conduct anticipatory COVID-19 ACP with their high-risk patients, which was associated with reduced COVID-19 treatment intensity. This underscores the need for effective identification and dissemination of clinical risk factors in the next pandemic to guide anticipatory decision making.
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