LBX2-AS1 in acceleration of glycolysis and cancer angiogenesis via miR-491-5p/MDK signaling axis in colorectal cancer: an experimental study

Q: What type of study is this?

This is a Experimental Study study.

Juan Wang; Chao Li; Guanghai Wu; Jing Xu

doi:10.1080/07853890.2025.2564284

December 12, 2025Annals of MedicineOpen Access

LBX2-AS1 in acceleration of glycolysis and cancer angiogenesis via miR-491-5p/MDK signaling axis in colorectal cancer: an experimental study

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Key Points

To investigate the role of LBX2-AS1 in glycolysis and angiogenesis in colorectal cancer.
Experimental study evaluating the impact of LBX2-AS1 on glycolysis and angiogenesis.
Analysis of the miR-491-5p/MDK signaling axis in colorectal cancer cells.
LBX2-AS1 promotes cancer angiogenesis.
LBX2-AS1 activates glycolysis through the miR-491-5p/MDK axis.

Implication

Experimental study finds LBX2-AS1 enhances glycolysis and angiogenesis in colorectal cancer, suggesting new diagnostic and therapeutic targets.

Abstract

This study demonstrates that LBX2-AS1 promotes CRC angiogenesis and activates the glycolysis via the miR-491-5p/MDK axis. LBX2-AS may serve as a novel diagnostic biomarker and potential therapeutic target for CRC.

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Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/694019222d562116f28f6a77 https://doi.org/10.1080/07853890.2025.2564284

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LBX2-AS1 in acceleration of glycolysis and cancer angiogenesis via miR-491-5p/MDK signaling axis in colorectal cancer: an experimental study

Key Points

Implication

Abstract

Discussion

Cite This Study

LBX2-AS1 in acceleration of glycolysis and cancer angiogenesis via miR-491-5p/MDK signaling axis in colorectal cancer: an experimental study

Key Points

Implication

Abstract

Discussion

Cite This Study

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