Drug-related pressure ulcers in hospitalised patients: a multicentre retrospective study in Japan identifying high-risk medications and patient characteristics.

Fumihiro Mizokami; Tomoyasu Kinoshita; Yusuke Sekine; Toshiaki Miyagawa; M Toriumi; Kohtaro Ooka; A Nakashima; Kengo FUKUDA; Mari Sadaoka; Hiromi Ishii; Hiroyuki Kadowaki; Katsuhito Iikura; Shinako Fujimoto; T Yamanouchi; Y Shiraishi; Toshiyuki Ozaki; Hideharu Tatebe; Tetsuya Fuse; Shigeki Ikushima; Soichiro Higashitsuji; Kazumi Kurachi; Zenzo Isogai

doi:10.1136/bmjopen-2025-105828

Key Points

To identify high-risk medications and patient characteristics associated with drug-related pressure ulcers (DRPUs) in hospitalized patients.
Multicentre retrospective study conducted in Japan.
Participants included hospitalized patients with reported drug-related pressure ulcers.
Data on medications, including polypharmacy and antipsychotic use, were analyzed.
Increased incidence of polypharmacy observed in the DRPU group.
Patients on new medications or with dose modifications showed higher rates of DRPUs.
Characteristic clinical patterns were identified that may help in future hypothesis generation.

Implication

Retrospective study shows increased polypharmacy in patients with drug-related pressure ulcers, suggesting key risk factors.

Abstract

Medication-related characteristics such as polypharmacy, initiation of new medications, dose modifications and use of antipsychotics were more frequently observed in the definite DRPU group. These descriptive findings may help characterise the clinical patterns of DRPUs and may inform future hypothesis generation.

Discussion

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Cite This Study

Mizokami et al. (2025) studied this question.

synapsesocial.com/papers/69401b262d562116f28f78f0 https://doi.org/10.1136/bmjopen-2025-105828

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Drug-related pressure ulcers in hospitalised patients: a multicentre retrospective study in Japan identifying high-risk medications and patient characteristics.

Key Points

Implication

Abstract

Discussion

Cite This Study

Drug-related pressure ulcers in hospitalised patients: a multicentre retrospective study in Japan identifying high-risk medications and patient characteristics.

Key Points

Implication

Abstract

Discussion

Cite This Study

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