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December 10, 2025New Journal of Chemistry

Unravelling the Mechanism of Phosphine-Catalyzed Azetine Formation and BF ₃ -Mediated Ring-Opening to Axially Chiral Alkenes: A DFT Study

Mengmeng Wang Bingli Wang Lina Ding

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Abstract

The recent experimental synthesis of 2-azetines and axially chiral alkenes via phosphine catalysis coupled with BF 3 ·Et 2 O/Et 3 SiH/H 2 O-mediated ring-opening presents a complex mechanistic puzzle. Key questions regarding the oversimplified reaction sequence, the...

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Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/69401b372d562116f28f7d9a https://doi.org/10.1039/d5nj04376j

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