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December 10, 2025Scientific ReportsOpen Access

A sex-adjusted 7-biomarker clinical aging clock for translational preventative medicine

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Authors

DMDavid H. MeyerGIGabriel Ibarra-MejíaAMAdrian Molière

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Overview

This analysis shows improved disease risk predictions in diverse populations, suggesting robust preventive care methods.

Key Points

  • The developed aging clock predicts disease risks using four validated biomarkers, enhancing preventive care based on health monitoring.
  • Analysis utilized blood biochemistry markers from over 59,000 samples in a Southeast Asian cohort, focusing on diverse populations.
  • Optimization involved a novel correction method, improving the accuracy for age-acceleration predictions and interpretability in aging processes.
  • This work supports a simple clock model that can inform personalized health strategies, allowing for practical application in clinical settings.

Cite This Study

Meyer et al. (2025) studied this question.

synapsesocial.com/papers/69401b372d562116f28f7ff8https://doi.org/10.1038/s41598-025-27478-9
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