What question did this study set out to answer?

This study aims to identify characteristics associated with epilepsy-caused deaths in adults with intellectual disability and epilepsy in England.

December 10, 2025Journal of Neurology Neurosurgery & Psychiatry

Epilepsy-related premature mortality in adults with intellectual disability in England: a population-based analysis

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Authors

RSRohit Shankar WHWilliam Henley SASharlene Allaudin

Discussion

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Overview

Population-based analysis shows epilepsy increases mortality in adults with intellectual disability, highlighting urgent need for systemic care improvements.

Key Points

This study aims to identify characteristics associated with epilepsy-caused deaths in adults with intellectual disability and epilepsy in England.
Retrospective population-based analysis of deaths reviewed by the English Learning from Lives and Deaths programme (2016–2021)
Deaths classified by primary cause being epilepsy or not
Multivariable Cox regression used to analyze associations with age at death and epilepsy-related mortality factors.
Epilepsy was the primary cause of death in 16.2% of deaths among adults with intellectual disability and epilepsy
Individuals with epilepsy died at a younger median age (56 years) compared to those with other causes (62 years)
Mortality more common among those with moderate-to-profound intellectual disability and ethnic minorities.
Risk factors included poor quality of care and lack of annual health checks, while psychiatric and SALT input was protective.

Cite This Study

Shankar et al. (2025) studied this question.

synapsesocial.com/papers/69401d472d562116f28f86aa https://doi.org/10.1136/jnnp-2025-337291

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December 10, 2025Journal of Neurology Neurosurgery & Psychiatry

Epilepsy-related premature mortality in adults with intellectual disability in England: a population-based analysis

View Full Paper

Ask AI

Bookmark

Authors

RSRohit Shankar WHWilliam Henley SASharlene Allaudin

Discussion

Member takes

Overview

Population-based analysis shows epilepsy increases mortality in adults with intellectual disability, highlighting urgent need for systemic care improvements.

Key Points

This study aims to identify characteristics associated with epilepsy-caused deaths in adults with intellectual disability and epilepsy in England.
Retrospective population-based analysis of deaths reviewed by the English Learning from Lives and Deaths programme (2016–2021)
Deaths classified by primary cause being epilepsy or not
Multivariable Cox regression used to analyze associations with age at death and epilepsy-related mortality factors.
Epilepsy was the primary cause of death in 16.2% of deaths among adults with intellectual disability and epilepsy
Individuals with epilepsy died at a younger median age (56 years) compared to those with other causes (62 years)
Mortality more common among those with moderate-to-profound intellectual disability and ethnic minorities.
Risk factors included poor quality of care and lack of annual health checks, while psychiatric and SALT input was protective.

Cite This Study

Shankar et al. (2025) studied this question.

synapsesocial.com/papers/69401d472d562116f28f86aa https://doi.org/10.1136/jnnp-2025-337291

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