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To investigate the relationship between thalamic damage and naming ability in left hemisphere stroke survivors.

December 9, 2025Neurobiology of LanguageOpen Access

Object Naming After Thalamic Damage: Evidence from a Large-Scale, Chronic-Phase Study of Left Hemisphere Stroke Survivors

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To investigate the relationship between thalamic damage and naming ability in left hemisphere stroke survivors.
Retrospective assessment of naming ability in 550 left-hemisphere chronic stroke survivors
Comparison of lesion sites: focal thalamic, combined thalamic and non-thalamic, and sparing the thalamus
Whole-brain lesion-symptom mapping and ridge regression to analyze contributions of brain regions.
Focal thalamic lesions not associated with chronic anomia.
Naming-related clusters identified in temporo-parietal and subcortical-insular regions.
Increased cognitive load may affect naming capability; further longitudinal studies recommended.

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Large-scale study reveals thalamic damage does not cause long-term anomia in stroke survivors, suggesting the role of cognitive load.

Zhang et al. (2025) studied this question.

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