Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 9, 2025International Journal of Clinical DermatologyOpen Access

Wells Syndrome (Eosinophilic Cellulitis): Current Clinical, Histopathological, and Therapeutic Aspects

View Full Paper
Ask AI
Bookmark
Share

Authors

NSNencho SmilovATAleksandar TrenovskiVBValentina Broshtilova

Discussion

Loading...

Member takes

Overview

Review finds diagnostic challenges and highlights therapeutic options for disease control in eosinophilic cellulitis.

Key Points

  • This review summarizes the clinical, histopathological, and therapeutic aspects of Wells syndrome.
  • Systematic analysis of classical and contemporary literature
  • Case series and clinical observations
  • Discussion of clinical presentation and histological characteristics
  • Disease presents with urticarial or annular plaques resembling cellulitis
  • Main treatment involves systemic corticosteroids, with alternatives like dapsone and methotrexate
  • Emerging biologic therapies targeting IL-5 and IL-4/IL-13 pathways show promise in managing the disorder.

Cite This Study

Smilov et al. (2025) studied this question.

synapsesocial.com/papers/69401efa2d562116f28f98a1https://doi.org/10.11648/j.ijcd.20250802.15
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1Immunofluorescence identification of eosinophil granule major basic protein in the flame figures of Wells' syndrome1983 · 122 citations