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December 9, 2025Circulation JournalOpen Access

Left Ventricular Ejection Fraction Improvement and Ventricular Arrhythmia Risk in Patients With Heart Failure

Toshihiro Nakamura Kohei Ishibashi Nobuhiko Ueda Tsukasa Oshima Satoshi Oka Yuichiro Miyazaki Akinori Wakamiya Kenzaburo Nakajima Tsukasa Kamakura Mitsuru Wada Yuko Inoue K. Miyamoto Takeshi Aiba Kengo Kusano

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Key Points

To investigate the relationship between LVEF recovery and ventricular arrhythmia risk in heart failure patients.
Examined the association between LVEF improvement and rates of ventricular arrhythmia
Focused on patients diagnosed with heart failure
Discussed implications for ICD management based on individual risk
LVEF recovery reduces ventricular arrhythmia risk
Improvements do not completely eliminate arrhythmia risk
Highlights need for individualized approaches to ICD management

Implication

Findings show LVEF improvement lowers ventricular arrhythmia risk in heart failure, suggesting tailored ICD management is vital.

Abstract

LVEF recovery reduces but does not eliminate ventricular arrhythmia risk, supporting individualized ICD management.

Discussion

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Cite This Study

Nakamura et al. (2025) studied this question.

synapsesocial.com/papers/69401efa2d562116f28f99a6 https://doi.org/10.1253/circj.cj-25-0814

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Left Ventricular Ejection Fraction Improvement and Ventricular Arrhythmia Risk in Patients With Heart Failurecohort · 2025
2Impact of Improved Left Ventricular Systolic Function on the Recurrence of Ventricular Arrhythmia in Heart Failure Patients With an Implantable Cardioverter‐Defibrillatorcohort · 2016 · 10 citations
3Arrhythmic Risk Following Recovery of Left Ventricular Ejection Fraction in Patients with Primary Prevention ICDcohort · 2016 · 9 citations
4Impact of Left Ventricular Ejection Fraction on Recurrent Ventricular Tachyarrhythmias in Recipients of Implantable Cardioverter Defibrillatorscohort · 2020 · 6 citations
5Comunicaçõescohort · 2026

More related papers

Left ventricular ejection fraction and myocardial fibrosis in survivors of ventricular fibrillation and ventricular tachycardia2024
Arrhythmic event prediction in patients with heart failure and reduced ejection fraction2020
Heart Failure with Recovered Ejection Fraction and the Utility of Defibrillator Therapy: A Review2021

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