Supramolecular Gelation of Hydrogen Peroxide: Reconciling Safety and Reactivity

Hydrogen peroxide (H 2 O 2 ) is a versatile green oxidant, but its industrial application is plagued by safety risks due to impurity‐induced exothermic decomposition and leakage. Conventional stabilizers compromise reactivity, creating a persistent safety‐reactivity paradox. Herein, this challenge is resolved through a supramolecular gelation strategy using a glycyrrhizic acid (GA) and polyvinyl alcohol (PVA) binary system, transforming aqueous H 2 O 2 into mechanically robust gels. The resulting gel exhibits exceptional mechanical strength (storage modulus >3600 Pa), thixotropy, and long‐term stability (>6 months), effectively eliminating leakage. Crucially, the gel matrix suppresses H 2 O 2 decomposition by up to 212‐fold in the presence of metal contaminants (e.g., Fe 3+ , Cu 2+ , MnO 2 ) by slowing convective mixing and isolating impurities via a bubble barrier, thereby preventing thermal runaway. Remarkably, the shear‐thinning properties of the gel enable the release of H 2 O 2 with uncompromised reactivity, achieving efficient sulfoxidation and alcohol oxidation with yields comparable to those of liquid H 2 O 2 . This work establishes supramolecular gelation as a transformative platform for the safe utilization of H 2 O 2 in industrial processes without sacrificing oxidative efficiency.