December 8, 2025The FASEB JournalOpen Access

Significant Enhancement of Adeno‐Associated Virus Vector Yield for Gene Therapy Using Multidimensional Optimization Strategies

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Significant enhancement of rAAV vector yield is achievable through optimization strategies, addressing key manufacturing costs.
The review highlights essential optimization in viral vectors, emphasizing genetic modification to improve gene therapy.
Assessment of optimization strategies for scalable adeno-associated virus vector manufacturing shows promise for genetic disorders.
These approaches aim to establish effective protocols for producing high-titer, clinical-grade adeno-associated virus preparations.

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Review explores genetic modification and manufacturing costs in viral vectors, suggesting optimization strategies for better gene therapy outcomes.

Shen et al. (2025) studied this question.

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Review explores genetic modification and manufacturing costs in viral vectors, suggesting optimization strategies for better gene therapy outcomes.