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December 8, 2025Advanced Synthesis & Catalysis

Late‐Stage Deaminative Radical Diversification of Sulfonamides via CuI/Photoredox Synergy: A Direct Strategy for (E)‐β‐Iodovinyl Sulfones

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Authors

CLCheng‐Liang LiuJLJia LiuJDJia‐Ying Dai

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Overview

This process utilizes copper to generate sulfonyl radicals from sulfonamides for iodination of alkynes, indicating enhanced synthetic efficiency.

Key Points

  • Iodination of alkynes with sulfonamides leads to efficient synthesis of sulfonyl compounds.
  • The method utilizes copper as a dual-function catalyst, streamlining sulfonamide transformations.
  • This protocol simplifies the process by avoiding prefunctionalization of sulfonamides, enhancing usability in diverse contexts.
  • The results may highlight new pathways for chemical synthesis in organic chemistry.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/694020e22d562116f28fa91ahttps://doi.org/10.1002/adsc.70068
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