Integration of chitosan nanocomposites improves bioavailability and therapeutic efficacy of mirtazapine, highlighting spray drying's role in drug delivery.
Key Points
This approach enhances bioavailability of mirtazapine for brain treatment via innovative drug delivery systems.
A 39-fold increase in brain C max illustrates the effectiveness of the nanocomposites compared to standard formulations.
Spray drying methodology optimizes the preparation of lecithin-coated mirtazapine nanocomposites for improved delivery.
Results indicate reduced serotonin levels and enhanced therapeutic efficacy, emphasizing the system's potential for treating brain disorders.