December 7, 2025BMC Psychology0 citationsOpen Access
Association between creatinine to cystatin C ratio and the incidence of depressive symptoms among middle-aged and older adults: insight from the CHARLS study
Lower creatinine to cystatin C ratio correlates with higher incidence of depressive symptoms over 2 years.
The study identified an inverse relationship, with significant implications for mental health management.
Assessment via the CHARLS study, which offers valuable data from middle-aged and older adults.
Findings support the potential role of the biomarker in predicting mental health outcomes among older adults.
Abstract
The CCR is inversely associated with the risk of incident DS over 2 years, suggesting that the CCR may serve as a useful biomarker for predicting and managing mental health in middle-aged and older adults.