Prenatal exposure to agricultural pesticide applications and gestational diabetes mellitus in the Az-PEARS population-based study (2014–2020)

Kimberly Parra; Robin B. Harris; Leslie V. Farland; Paloma I. Beamer; Peter C. Ellsworth

doi:10.1016/j.envint.2025.109989

December 7, 2025Environment InternationalOpen Access

Prenatal exposure to agricultural pesticide applications and gestational diabetes mellitus in the Az-PEARS population-based study (2014–2020)

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Key Points

Gestational diabetes risk increases with prenatal exposure to organophosphates and related pesticides, highlighting significant findings.
Key evidence indicates higher GDM risk linked to organophosphate exposure during T3 of gestation.
Analysis performed on data from the Az-PEARS population-based study between 2014 and 2020.
Implications underscore the importance of timing regarding pesticide exposure and pregnancy outcomes.

Implication

Observational analysis linked organophosphates and prenatal exposure to increased GDM risk, suggesting critical exposure windows.

Abstract

Exposure to pyrethroids in T0, and organophosphates in T3 are associated with higher GDM risk. Our findings suggest that critical windows of pesticide exposure may be important considerations for GDM risk.

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Cite This Study

Parra et al. (2025) studied this question.

synapsesocial.com/papers/694020ee2d562116f28fafe7 https://doi.org/10.1016/j.envint.2025.109989

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Prenatal exposure to agricultural pesticide applications and gestational diabetes mellitus in the Az-PEARS population-based study (2014–2020)

Key Points

Implication

Abstract

Discussion

Cite This Study

Prenatal exposure to agricultural pesticide applications and gestational diabetes mellitus in the Az-PEARS population-based study (2014–2020)

Key Points

Implication

Abstract

Discussion

Cite This Study

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