Observational analysis revealed no difference in opioid overdose or use in two cities, indicating limitations of motivational interviewing.
Researchers have found that REBOOT, a repeated dose motivational interviewing intervention, had a statistically significant effect on opioid overdose in two cities — San Francisco and Boston — where fentanyl was the main street opioid. According to the report, published in Addiction on Nov. 19, this intervention doesn't work in the era of fentanyl. Compared with a control group, there were no differences in opioid use or overdoses.
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Alison Knopf (2025) studied this question.
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