Cross-sectional study shows endothelial activation may indicate cognitive decline risk in older adults, suggesting clinical utility for screening.
EASIX is significantly negatively associated with cognitive function, especially in advanced age. Although the cross-sectional design precludes causal inference, it shows promise as a blood-based biomarker for early screening and risk assessment of cognitive decline, supporting its potential clinical utility.
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Wang et al. (2025) studied this question.
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