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Analysis reveals salidroside activates signaling pathway to reduce cerebral ischemia-reperfusion injury, suggesting a potential intervention strategy.
Salidroside may inhibit iron death by activating the PINK 1 / Parkin signaling pathway and thereby reduce cerebral ischemia-reperfusion injury. Targeted regulation of this pathway may become an important strategy to interfere with CIRI.
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Dong et al. (2025) studied this question.
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