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December 5, 2025Journal of Bone and Joint Infection0 citationsOpen Access

Causes of Death After Revision for Periprosthetic Joint Infection or Aseptic Failure in Hip and Knee

Cause of death following revision for periprosthetic joint infection or major aseptic revision in total hip and knee arthroplasty

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Authors

NKNicolai Kjældgaard KristensenAPAlma B Pedersen

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Overview

Observational analysis identified higher comorbidity burden and musculoskeletal disease deaths in PJI revisions, suggesting multifactorial mortality causes post-surgery.

Key Points

  • Infections and musculoskeletal diseases were more frequent causes of death in patients revised for periprosthetic joint infection.
  • Among deceased patients, 37% underwent revision for periprosthetic joint infection, highlighting significant mortality differences.
  • Analysis utilized inverse probability of treatment weighting for confounding adjustments based on health registry data.
  • Mortality post-revision may involve various interconnected causes, implying a need for comprehensive post-operative care.

Cite This Study

Kristensen et al. (2025) studied this question.

synapsesocial.com/papers/694022442d562116f28fbad0https://doi.org/10.5194/jbji-10-543-2025
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