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December 5, 2025TomographyOpen Access

Quantitative Magnetic Resonance Imaging of the Forearm in Myotonic Dystrophy Type 1

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Authors

KCKorey D. CookeUniversity of FloridaKVKrista VandenborneAmerican College of Sports MedicineSSS. H. SubramonyMuscular Dystrophy Association

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Overview

Quantitative MRI measures show significant correlations with function and myotonia in patients with myotonic dystrophy type 1, suggesting new assessment approaches.

Key Points

  • Quantitative MRI assessments can effectively reveal correlations with upper extremity function in patients.
  • Significant correlations for fat fraction and T2 relaxation time were found across muscle measurements.
  • Data collected from eighteen adult patients highlights the flexor digitorum profundus as particularly affected.
  • Using quantitative MRI may help in monitoring therapeutic treatments and advancing patient care options.

Cite This Study

Cooke et al. (2025) studied this question.

synapsesocial.com/papers/6940224e2d562116f28fbfbahttps://doi.org/10.3390/tomography11120136
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Also Consider

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  1. 1Muscle MRI of the Upper Extremity in the Myotonic Dystrophy Type 12016 · 16 citations
  2. 2Whole-body quantitative muscle MRI in myotonic dystrophy type 2: a sensitive tool for pattern recognition, disease stratification and objective assessment of clinical severity2026
  3. 3Upper and Lower Extremities in Duchenne Muscular Dystrophy Evaluated with Quantitative MRI and Proton MR Spectroscopy in a Multicenter Cohort2020 · 43 citations
  4. 4Muscle MRI as a biomarker of disease activity and progression in myotonic dystrophy type 1: a longitudinal study2024 · 9 citations
  5. 5<scp>3D</scp> Radiomic Texture Analysis of Quantitative Muscle <scp>MRI</scp> Enhances the Distinction Between Myotonic Dystrophy Type 1 and Charcot–Marie‐Tooth Neuropathy Type <scp>1A</scp> : A Proof‐of‐Concept Study2026