Cationic halogenated BODIPYs as water-soluble photosensitizers for photodynamic therapy | Synapse
December 5, 2025
Cationic halogenated BODIPYs as water-soluble photosensitizers for photodynamic therapy
Key Points
Cationic halogenated BODIPYs achieve strong light-triggered cytotoxicity in cancer cells, and accumulate efficiently within them.
The innovative dye platform generates reactive oxygen, enhancing the effectiveness of photodynamic therapy in targeted cancer treatment.
Assessment using fluorescence imaging reveals clear intracellular fluorescence, indicating a robust accumulation of the BODIPYs.
This approach highlights potential advancements in cancer therapy, possibly offering new strategies in photosensitizer applications.
Abstract
A halogenated cationic dye platform generates reactive oxygen efficiently and accumulates in cancer cells, enabling strong light-triggered cytotoxicity with clear intracellular fluorescence.