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December 5, 2025Scientific ReportsOpen Access

Association between blood urea nitrogen-to-creatinine ratio and 28-day mortality in acute kidney injury patients undergoing continuous renal replacement therapy

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SGShuiqing GuiShenzhen Second People's Hospital ZZZhi-Ye ZouShenzhen Second People's Hospital

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Implication

Retrospective cohort study finds elevated BUN/Cr ratio linked to increased 28-day mortality risk in acute kidney injury patients, suggesting a prognostic marker for intervention.

Key Points

Increased mortality risk associated with elevated BUN/Cr ratio in acute kidney injury patients.
Patients with the highest BUN/Cr quartile had a hazard ratio of 1.66 with 28-day mortality, indicating significantly elevated risk.
Analysis using multivariate Cox regression and Kaplan-Meier evaluated the BUN/Cr ratio's impact on mortality.
Findings emphasize the BUN/Cr ratio as a potential prognostic marker for guiding interventions in acute kidney injury patients.

Cite This Study

Gui et al. (2025) studied this question.

synapsesocial.com/papers/694022532d562116f28fc492 https://doi.org/10.1038/s41598-025-31527-8

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Implication

Retrospective cohort study finds elevated BUN/Cr ratio linked to increased 28-day mortality risk in acute kidney injury patients, suggesting a prognostic marker for intervention.

Association between blood urea nitrogen-to-creatinine ratio and 28-day mortality in acute kidney injury patients undergoing continuous renal replacement therapy

Discussion

Member takes

Implication

Key Points

Cite This Study

Association between blood urea nitrogen-to-creatinine ratio and 28-day mortality in acute kidney injury patients undergoing continuous renal replacement therapy

Discussion

Member takes

Implication

Key Points

Cite This Study

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