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December 3, 2025The International Journal of Gastroenterology and Hepatology Diseases

The Spectrum of De Novo Malignancies After Liver Transplantation: A Review on Current Trends and Surveillance

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Authors

MUMario UribeHospital del Salvador

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Implication

This review highlights the increased risk of de novo malignancies in liver transplantation recipients, suggesting tailored surveillance and management strategies.

Key Points

  • De novo malignancies are a leading cause of late mortality after liver transplantation.
  • Nonmelanoma skin cancers account for 35–40% of all de novo malignancies post-transplant.
  • Immunosuppression and chronic viral infections are significant risk factors for cancer development.
  • Implementation of early detection and screening protocols may improve long-term patient outcomes.

Cite This Study

Mario Uribe (2025) studied this question.

synapsesocial.com/papers/694025972d562116f28fea56https://doi.org/10.2174/0126662906402878251122062713
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Also Consider

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  1. 1Viral carcinogenesis: revelation of molecular mechanisms and etiology of human disease2000 · 373 citations
  2. 2Colorectal cancer incidence trends in younger versus older adults: an analysis of population-based cancer registry data2024 · 358 citations
  3. 3Spectrum of Cancer Risk Among US Solid Organ Transplant Recipients2011 · 1,535 citations
  4. 4De Novo Malignancy After Liver Transplantation: Risk Assessment, Prevention, and Management—Guidelines From the ILTS-SETH Consensus Conference2021 · 83 citations
  5. 5Cumulative exposure to tacrolimus and incidence of cancer after liver transplantation2022 · 111 citations