December 3, 2025PLoS ONEOpen Access

Lesion volume and location can be estimated by analysis of the new NIH Stroke Scale picture description

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Acute ischemic stroke patients exhibited varied discourse linked to lesion location and severity, highlighting language impairment.
Those with left hemisphere strokes included less content from the right side of the picture, F(2)=7.4, p=0.001.
Analysis was performed using diffusion-weighted imaging to measure lesion impacts on language processing and discourse characteristics.
Findings support the validity of the new Precarious Painter picture description in assessing stroke location and severity.

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Analysis reveals changes in language processing and stroke severity based on lesion location in patients with acute ischemic stroke.

Stockbridge et al. (2025) studied this question.

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