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December 2, 2025BMC Medical EthicsOpen Access

How to improve informed consent processes in clinical trials with cancer patients: a qualitative analysis of multidisciplinary experts’ perspectives

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Authors

CBChristine BernardiDWDaniel WolffFLFlorian Lüke

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Overview

Qualitative analysis reveals expert perspectives on enhancing informed consent and communication in cancer trials, indicating potential strategies to reduce anxiety and improve patient understanding.

Key Points

  • Improved informed consent processes may enhance understanding for cancer patients during clinical trials, reducing anxiety.
  • Qualitative analysis involved 17 semi-structured interviews with multidisciplinary experts in oncology and communication.
  • Experts highlighted the challenge of legalistic informed consent documents that may hinder patient understanding and engagement.
  • Implementation of evidence-based strategies like checklists and nursing staff involvement could facilitate better communication in clinical trials.

Cite This Study

Bernardi et al. (2025) studied this question.

synapsesocial.com/papers/6940259e2d562116f28fee71https://doi.org/10.1186/s12910-025-01348-5
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Improving Clinical Communication: a qualitative study on the Informed Consent2024 · 3 citations
  2. 2Four reasons why too many informed consents to clinical research are invalid: a critical analysis of current practices2022 · 22 citations
  3. 3Measuring and evaluating participant understanding of consent processes in clinical trials: a systematic review2026 · 1 citations
  4. 4Informed consent in cancer clinical care: Perspectives of healthcare professionals on information disclosure at a tertiary institution in Uganda2024 · 5 citations
  5. 5Measuring and evaluating participant understanding of consent processes in clinical trials: a systematic review2025