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Genome-wide association study uncovers genetic factors impacting lung function decline in a Korean cohort, suggesting new predictive tools.
Our study identified novel SNPs associated with FEV₁ decline and developed a GRS that could help predict individuals at higher risk of rapid FEV₁ decline. The influence of genetic factors on the annual rate of decline in FEV₁ may vary depending on phenotypic characteristics.
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Bae et al. (2025) studied this question.
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