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Consensus document outlines management strategies for cholestasis in children, highlighting the role of biliary atresia and the importance of early detection.
Cholestasis is indicative of hepatobiliary dysfunction and is always pathological. Early detection helps improve the prognosis of some of the underlying diseases that cause it. The most common liver disease that causes cholestasis in the first months of life is biliary atresia, followed by monogenic diseases. The objective of this document is to provide consensus-based recommendations for the adequate management of cholestasis based on the review of the current evidence. A working group was created for the purpose, with participation of members of the Spanish Society of Pediatric Gastroenterology, Hepatology and Nutrition, the Spanish Association of Primary Care Pediatrics and the Spanish Society of Primary Care Pediatrics. The group established 26 recommendations to guide management in everyday clinical practice in both primary care and hospital settings.
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Mercadal‐Hally et al. (2025) studied this question.
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